Depression: Natural Support with Eicosapentaenoic Acid (EPA)

Self-Directed CPD


Number 122. For Professional Use Only

Essential fatty acids (EFAs) are required for maintenance of optimal health but they cannot be synthesized by the body and must be obtained from dietary sources.1 Fish oils are a rich source of omega-3 polyunsaturated fatty acids (ω-3 PUFAs), in particular eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA). Low levels of ω-3 PUFAs have been linked to depression2,3 and suicide4 as well as to cardiovascular5,6 and inflammatory disorders7 and this may therefore impact comorbidity of depression with diseases such as coronary heart disease8,9 and diabetes.10 Specifically EPA has been studied for its role in depressive disorders and reducing cellular inflammation.

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